Gisella Perl showed academic promise at a young age. At the age of 16 she was the only woman—and the only Jewish person—to graduate from her secondary school. She had great academic aspirations, and approached her father requesting to go to medical school. Her father was hesitant, not wanting his daughter to lose her faith and leave Judaism. She did not relent. In a 1982 interview with the New York Times, Perl recounted returning to her father months later, this time holding a prayer book her father had given her, “I swear on this book that wherever life will take me, under whatever circumstance, I shall always remain a good, true Jew.” Her father gave in, and years later when she was paid by her first patient, she bought him a prayer book with his named engraved in it.
In 1944, Dr. Perl was working as a gynecologist, had just married a surgeon and was living in a Jewish ghetto with her family in Hungary (modern-day Romania). In March of that year, Dr. Perl and her husband, son, parents and extended family were sent to Auschwitz, where they were immediately separated. Her young daughter, however, was hidden with a non-Jewish family. Dr. Joseph Mengele—the German physician and SS Captain of Auschwitz—assigned Dr. Perl to work in the hospital.